Melanotan-II

Melanotan-II is a synthetic cyclic heptapeptide analogue of alpha-melanocyte stimulating hormone (α-MSH) with Nle4, D-Phe7 substitutions and a lactam-bridged cyclic structure. It has been referenced in published preclinical literature and is manufactured to ≥99% purity with third-party verification.

Melanotan-II is a synthetic cyclic heptapeptide α-MSH analogue with Nle4, D-Phe7 substitutions and a lactam-bridged structure. Developed at the University of Arizona, it has been referenced in published preclinical literature. Supplied as a high-purity lyophilized research peptide.

Melanotan-II was developed at the University of Arizona by researchers including Victor Hruby and Mac Hadley during the 1980s and 1990s. It was derived from the same Nle4, D-Phe7 α-MSH template as Melanotan-1, but engineered with a lactam bridge to create a distinct cyclic structure.

This peptide carries the True Research Certified designation, awarded exclusively to compounds that achieve verified ≥99% purity through independent third-party HPLC and mass spectrometry analysis. True Research Certified products undergo batch-level endotoxin screening via the LAL (Limulus Amebocyte Lysate) method and are accompanied by a comprehensive Certificate of Analysis (COA) documenting purity, identity, and endotoxin results. This certification reflects our commitment to supplying only the highest-grade research materials to the scientific community.